Abstract
We report the complete genome sequence of Acinetobacter baumannii strain AbH12O-A2, isolated during a large outbreak in Spain. The genome has 3,875,775 bp and 3,526 coding sequences, with 39.4% G+C content. The availability of this genome will facilitate the study of the pathogenicity of the Acinetobacter species.
Highlights
Acinetobacter baumannii is a major cause of hospital-acquired infections
During 2006 –2008, 377 patients were colonized/infected with multiresistant A. baumannii strains in a hospital in Madrid, Spain
This was one of the most important nosocomial outbreak produced by A. baumannii known to date [1, 2]
Summary
Acinetobacter baumannii is a major cause of hospital-acquired infections. During 2006 –2008, 377 patients were colonized/infected with multiresistant A. baumannii strains in a hospital in Madrid, Spain. The clones isolated during the outbreak harbored different plasmids, all containing a blaOXA-24 gene mobilized through a Xer recombination mechanism. Two mutations found to modify the gene expression of virulence factors provided an advantage to strain AbH12O-A2, whose genome sequence is described here.
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