Abstract
Polioviruses are the major etiological agents associated with acute flaccid paralysis (AFP). The complete genome sequence of a representative of the last wild poliovirus type 1 genotype isolated in Brazil from a paralytic poliomyelitis case is reported here.
Highlights
Polioviruses are the major etiological agents associated with acute flaccid paralysis (AFP)
Polioviruses belong to the genus Enterovirus, family Picornaviridae, are among the most important and well-studied human pathogens, and are the etiologic agents of paralytic poliomyelitis [1, 2]
The oral poliovirus vaccine (OPV) was introduced into the routine immunization program for infants in Brazil in the early 1960s, the circulation of wild poliovirus dropped sharply only after the implementation of National Immunization Days (NIDs) in 1980, which set the goal of vaccinating in a single day, twice a year, the entire population of children Ͻ5 years of age, irrespective of their vaccination history [3, 4]
Summary
Polioviruses are the major etiological agents associated with acute flaccid paralysis (AFP). Polioviruses belong to the genus Enterovirus, family Picornaviridae, are among the most important and well-studied human pathogens, and are the etiologic agents of paralytic poliomyelitis [1, 2]. The oral poliovirus vaccine (OPV) was introduced into the routine immunization program for infants in Brazil in the early 1960s, the circulation of wild poliovirus dropped sharply only after the implementation of National Immunization Days (NIDs) in 1980, which set the goal of vaccinating in a single day, twice a year, the entire population of children Ͻ5 years of age, irrespective of their vaccination history [3, 4].
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