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Abstract
ABSTRACTThe complete genome sequence of foot-and-mouth disease virus (FMDV) serotype Asia1 isolated from Bangladesh is reported here. Genome analysis revealed amino acid substitutions in the VP1 antigenic region and deletions in both the 5′ and 3′ untranslated regions (UTRs) compared to the genome of the existing vaccine strain (GenBank accession no. AY304994).
Highlights
The complete genome sequence of foot-and-mouth disease virus (FMDV) serotype Asia[1] isolated from Bangladesh is reported here
We report here the first complete genome sequence of an FMDV serotype Asia[1] isolate, BAN/TA/Ma-167/2013, collected from the tongue epithelium of ruptured vesicles of an infected cow on 23 July 2013 at Madhupur, Tangail, Bangladesh
The VP1 phylogeny clustered the strain within genetic lineage C, which corroborates our previous report describing the circulation of monotypic FMDV Asia[1] in Bangladesh (6)
Summary
The complete genome sequence of foot-and-mouth disease virus (FMDV) serotype Asia[1] isolated from Bangladesh is reported here. We report here the first complete genome sequence of an FMDV serotype Asia[1] isolate, BAN/TA/Ma-167/2013, collected from the tongue epithelium of ruptured vesicles of an infected cow on 23 July 2013 at Madhupur, Tangail, Bangladesh. Virus isolation was performed in the BHK-21 cell line, viral RNA was extracted from the infected cell culture supernatant at passage 3, and cDNA was synthesized with random and oligo(dT) primers.
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