Abstract
The complete genome sequence of Seneca Valley virus (SVV), a single-stranded RNA virus that causes porcine vesicular disease in China, has been sequenced and analyzed. This Chinese isolate shares 94.4 to 97.1% sequence identity to another 8 strains from Canada, Brazil, and the United States. This is the first report of SVV infecting swine in China.
Highlights
The complete genome sequence of Seneca Valley virus (SVV), a single-stranded RNA virus that causes porcine vesicular disease in China, has been sequenced and analyzed
Seneca Valley virus (SVV), which causes porcine idiopathic vesicular disease, was first identified in either contaminated fetal bovine serum or porcine trypsin during the cultivation of PER.C6 cells [1] and isolated from pigs displaying suspicious vesicular disease when pigs were imported to the United States from Canada in 2007 [2, 3]
The complete genome of SVV CH-01-2015 was generated with reverse transcriptase PCR (RT-PCR) using 7 pairs of primers amplifying 7 overlapped fragments
Summary
The complete genome sequence of Seneca Valley virus (SVV), a single-stranded RNA virus that causes porcine vesicular disease in China, has been sequenced and analyzed. Seneca Valley virus (SVV), which causes porcine idiopathic vesicular disease, was first identified in either contaminated fetal bovine serum or porcine trypsin during the cultivation of PER.C6 cells [1] and isolated from pigs displaying suspicious vesicular disease when pigs were imported to the United States from Canada in 2007 [2, 3]. It has been identified in Canada and Brazil [4, 5].
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