Abstract
Lysinibacillus sphaericus is a species that contains strains widely used in the biological control of mosquitoes. Here, we present the complete 4.67-Mb genome of the WHO entomopathogenic reference strain L. sphaericus 2362, which is probably one of the most commercialized and studied strains. Genes coding for mosquitocidal toxin proteins were detected.
Highlights
Lysinibacillus sphaericus is a species that contains strains widely used in the biological control of mosquitoes
L. sphaericus strain 2362 was isolated in 1984 from adult Simulium damnosum samples in Nigeria and it was determined to belong to serotype 5a5b and phagotype 3
In spite of the above, the genome of L. sphaericus 2362 has not been available until now, and only 13 genomes are deposited in GenBank for this bacterium
Summary
Lysinibacillus sphaericus is a species that contains strains widely used in the biological control of mosquitoes. After its grade of mosquitocidal activity was confirmed, this strain was introduced into the WHO Collaborating Centre (Columbus, OH, USA) [2]. This strain has been extensively used, as a reference in research about larvicidal activity of L. sphaericus [1, 3], and as a point of comparison for studying metal tolerance [4, 5], the structure of surface proteins such as the S-layer [6, 7], and biosurfactant production [8].
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