Abstract

Klebsiella pneumoniae is a Gram-negative pathogen frequently associated with antibiotic-resistant nosocomial infections. Bacteriophage therapy against K. pneumoniae may be possible to combat these infections. The following describes the complete genome sequence and key features of the pseudo-T-even K. pneumoniae carbapenemase (KPC)-producing K. pneumoniae myophage Miro.

Highlights

  • Klebsiella pneumoniae is a Gram-negative pathogen frequently associated with antibiotic-resistant nosocomial infections

  • Bacteriophage Miro was isolated from a sewage sample collected at College Station, TX, based on its ability to grown on K. pneumoniae carbapenemase (KPC)-producing K. pneumoniae strain A1

  • Morphology was determined using transmission electron microscopy performed at the Texas A&M University Microscopy and Imaging Center

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Summary

Introduction

Klebsiella pneumoniae is a Gram-negative pathogen frequently associated with antibiotic-resistant nosocomial infections. We describe the complete genome of pseudo-T-even myophage Miro. Bacteriophage Miro was isolated from a sewage sample collected at College Station, TX, based on its ability to grown on KPC-producing K. pneumoniae strain A1. Phage DNA was sequenced in an Illumina MiSeq 250-bp paired-end run with a 550-bp insert library at the Genomic Sequencing and Analysis Facility at the University of Texas (Austin, TX).

Results
Conclusion

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