Abstract
Helicobacter pylori-induced gastritis is a risk factor for developing gastric pathologies. Here, we report the complete genome sequence of a multidrug-resistant H. pylori strain isolated from a chronic gastritis patient in Mexico City, Mexico. Nonvirulent VacA and cag-pathogenicity island (PAI) genotypes were found, but the presence of a potential mobilizable plasmid carrying an IS605 element is of outstanding interest.
Highlights
Helicobacter pylori infection produces chronic gastritis and increases the risk of peptic ulcer, gastric cancer, and mucosaassociated lymphoid tissue (MALT) lymphoma due to the bacterial interaction between its virulence factors and the cellular components of the host [1, 2]
Whether the genome structure of the H. pylori strains isolated in Mexico is similar to that of the strains isolated worldwide or not remains unknown, as only one genome of H. pylori isolated in Mexico has been sequenced [3]
We present the complete genome sequence of H. pylori strain 7C, which was isolated from a patient with chronic gastritis in Mexico City, Mexico
Summary
Helicobacter pylori infection produces chronic gastritis and increases the risk of peptic ulcer, gastric cancer, and mucosaassociated lymphoid tissue (MALT) lymphoma due to the bacterial interaction between its virulence factors and the cellular components of the host [1, 2]. Whether the genome structure of the H. pylori strains isolated in Mexico is similar to that of the strains isolated worldwide or not remains unknown, as only one genome of H. pylori isolated in Mexico has been sequenced [3]. We present the complete genome sequence of H. pylori strain 7C, which was isolated from a patient with chronic gastritis in Mexico City, Mexico.
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