Abstract
The complete genome sequence of a foot-and-and mouth disease virus (FMDV) type A strain (BAN/GA/Sa-197/2013), isolated from Gazipur in Bangladesh, revealed an 84-nucleotide insertion within the 5′-untranslated region (UTR), a lengthened poly(C) tract, and amino acid substitutions at the VP1 region compared to the available genome sequence of the vaccine strain (GenBank accession no. HM854025).
Highlights
The complete genome sequence of a foot-and-and mouth disease virus (FMDV) type A strain (BAN/GA/Sa-197/2013), isolated from Gazipur in Bangladesh, revealed an 84-nucleotide insertion within the 5=-untranslated region (UTR), a lengthened poly(C) tract, and amino acid substitutions at the VP1 region compared to the available genome sequence of the vaccine strain
Foot-and-mouth disease virus (FMDV), a single-stranded positive-sense RNA virus belonging to the Picornaviridae family and genus Aphthovirus, is highly infectious and causes disease in domestic and wild cloven-hoofed animals
FMDV serotype A is grouped into the topotypes Asia, Europe-South America, and Africa based on genotyping, and it seems to be the most genetically and antigenically diverse among all FMDV serotypes [2, 3]
Summary
The complete genome sequence of a foot-and-and mouth disease virus (FMDV) type A strain (BAN/GA/Sa-197/2013), isolated from Gazipur in Bangladesh, revealed an 84-nucleotide insertion within the 5=-untranslated region (UTR), a lengthened poly(C) tract, and amino acid substitutions at the VP1 region compared to the available genome sequence of the vaccine strain Foot-and-mouth disease virus (FMDV), a single-stranded positive-sense RNA virus belonging to the Picornaviridae family and genus Aphthovirus, is highly infectious and causes disease in domestic and wild cloven-hoofed animals. The characteristic feature of FMDV, like other RNA viruses, is that it is genetically diverse and includes seven distinct serotypes (O, A, C, Asia-1, and SAT 1 to 3) and multiple subtypes worldwide [1].
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
