Abstract
The emergence of vancomycin-resistant enterococci (VRE) has been associated with an increase in multidrug-resistant nosocomial infections. Here, we report the 2.614-Mb genome sequence of the Enterococcus faecium commensal isolate E1002, which will be instrumental in further understanding the determinants of the commensal and pathogenic lifestyle of E. faecium.
Highlights
The emergence of vancomycin-resistant enterococci (VRE) has been associated with an increase in multidrug-resistant nosocomial infections
Enterococcus faecalis and E. faecium are considered as commensal bacteria of the human microbiota [1]
E. faecalis was responsible for over 90% of all enterococcal infections, but since the 1980s the number of infections by E. faecium has increased and nowadays both species are frequently found as causative agents of nosocomial infections
Summary
The emergence of vancomycin-resistant enterococci (VRE) has been associated with an increase in multidrug-resistant nosocomial infections. Enterococcus faecalis and E. faecium are considered as commensal bacteria of the human microbiota [1]. Some members of these species have evolved into important nosocomial threats, partially due to the acquisition of antibiotic resistance cassettes [2]. E. faecalis was responsible for over 90% of all enterococcal infections, but since the 1980s the number of infections by E. faecium has increased and nowadays both species are frequently found as causative agents of nosocomial infections.
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