Abstract
We report here the first characterized complete genome sequence of porcine circovirus types 2a and 2b from northeastern states of India. These isolates may serve as a potential reference for the Indian strains of porcine circovirus types 2a and 2b.
Highlights
Porcine circovirus-2 (PCV-2), a member of the Circovirade family, is a small, nonenveloped single stranded circular DNA virus
The circular genome (1,767 to 1,768 bp) of PCV-2 is comprised of three major open reading frames (ORFs), i.e., ORF-1 which encodes the replication protein, ORF-2 considered as a phylogenetic marker and encodes the capsid protein, and ORF-3 which encodes the apoptotic protein [4]
PCV-2 is subdivided into three genotypes based on their ORF-2 gene, PCV-2a, PCV-2b, and PCV-2c [5, 6]
Summary
Porcine circovirus-2 (PCV-2), a member of the Circovirade family, is a small, nonenveloped single stranded circular DNA virus. PCV-2 is considered an important emerging pathogen for global swine industries with several disease manifestations that are collectively called PCV-2-associated disease (PCVAD) and include post weaning multisystemic wasting syndrome (PMWS) [1]. PMWS was first reported in 1997 in Canada and subsequently from other countries including India [2, 3].
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