Abstract
Clostridium septicum is one of the first pathogenic anaerobes to be identified. Here, we announce the genome draft sequence of C. septicum strain CSUR P1044 isolated from the gut of a healthy adult. Its chromosome genome consists of 3.2 Mbp with a plasmid of 32 Kbp. C. septicum strain CSUR P1044 has a G+C content of 27.5%, and is composed of 3,125 protein-coding genes together with 103 RNA genes, including 22 rRNA genes.
Highlights
Clostridium septicum is one of the first pathogenic anaerobes to be identified
C. septicum is recognized as a causative agent of both traumatic and nontraumatic gas gangrene, but cases of arthritis and aortitis have been described [2,3,4]
The major virulence factor produced by C. septicum is a pore-forming alpha-toxin encoded by the csa gene, which appears to be carried by all strains of this bacterium [7]
Summary
Clostridium septicum is one of the first pathogenic anaerobes to be identified. Here, we announce the genome draft sequence of C. septicum strain CSUR P1044 isolated from the gut of a healthy adult. Clostridium septicum, a Gram-positive, spore-forming bacillus, is the first anaerobic opportunistic bacterium ever cultivated, discovered by Pasteur in 1877 [1]. It has been reported to be present in the environment and in the gut microbiota of humans and animals [2]. The major virulence factor produced by C. septicum is a pore-forming alpha-toxin encoded by the csa gene, which appears to be carried by all strains of this bacterium [7].
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