Abstract

Reported herein is the complete genome sequence of the type strain B-78 (ATCC 27164) of Brachyspira hyodysenteriae, the etiological agent of swine dysentery. The 3.1-Mb genome consists of a 3.056-Mb chromosome and a 45-kb plasmid, with 2,617 protein-coding genes, 39 RNA genes, and 40 pseudogenes.

Highlights

  • Reported is the complete genome sequence of the type strain B-78 (ATCC 27164) of Brachyspira hyodysenteriae, the etiological agent of swine dysentery

  • Brachyspira hyodysenteriae, is a Gram-negative and oxygen-tolerant anaerobic spirochetal bacterium that was first identified as the cause of swine dysentery in 1971 [2]

  • Despite the significance of the disease, no complete genomes of B. hyodysenteriae originating from the United States are currently available

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Summary

Introduction

Reported is the complete genome sequence of the type strain B-78 (ATCC 27164) of Brachyspira hyodysenteriae, the etiological agent of swine dysentery. Swine dysentery is an infectious disease that has a significant impact on the health, welfare, and productivity of pigs globally due to its clinical signs of bloody diarrhea, weakness, inappetence, and decreased weight gain [1]. Brachyspira hyodysenteriae, is a Gram-negative and oxygen-tolerant anaerobic spirochetal bacterium that was first identified as the cause of swine dysentery in 1971 [2]. Despite being a prevalent pathogen throughout most of the 20th century, the disease largely disappeared from the United States in the early 1990s and reemerged in the late 2000s [3].

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