Abstract
Bacillus bombysepticus is a Gram-positive spore-forming bacterium. Here, we announce the first complete genome sequence of this organism isolated from the cadavers of silkworm larvae that had been sick. The genome contains a single circular chromosome and a circular plasmid. Analyses of the B. bombysepticus genome will provide insights into its pathomechanisms and biology.
Highlights
Bacillus bombysepticus is a Gram-positive spore-forming bacterium
Infection with B. bombysepticus, a main bacterial pathogen of the silkworm, leads to the classical symptoms of black chest septicemia: a peutz appears on the thoracoabdominal region or the 1st to 3rd segment of the abdomen and expands to the whole body
Previous experiments demonstrated that many genes and pathways of the silkworm are modulated after B. bombysepticus infection [2, 3]
Summary
Bacillus bombysepticus is a Gram-positive spore-forming bacterium. Here, we announce the first complete genome sequence of this organism isolated from the cadavers of silkworm larvae that had been sick. Bacillus bombysepticus is a Gram-positive bacterium first identified by Hartman [1] from the corpses of silkworms (Bombyx mori) that had been sick. Infection with B. bombysepticus, a main bacterial pathogen of the silkworm, leads to the classical symptoms of black chest septicemia: a peutz appears on the thoracoabdominal region or the 1st to 3rd segment of the abdomen and expands to the whole body. Previous experiments demonstrated that many genes and pathways of the silkworm are modulated after B. bombysepticus infection [2, 3].
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