Abstract
ABSTRACTHere, we report the complete genome sequence of Bifidobacterium pseudolongum strain UMB-MBP-01, isolated from the feces of C57BL/6J mice. This strain was identified in microbiome profiling studies and associated with improved transplant outcome in a murine model of cardiac heterotypic transplantation.
Highlights
Members of the Bifidobacterium genus are high-GϩC Gram-positive bacteria that were first isolated and described over a century ago from the feces of breastfed infants [1]
The use of in vivo murine models to characterize the impact of specific members of the intestinal microbiota on the host physiology is a promising avenue for dissecting the key pathways involved in these interactions [3, 10]
Despite the availability of 386 Bifidobacterium wholegenome sequences in public databases, there has been no complete B. pseudolongum genome sequence obtained from a mouse isolate
Summary
Members of the Bifidobacterium genus are high-GϩC Gram-positive bacteria that were first isolated and described over a century ago from the feces of breastfed infants [1]. The use of in vivo murine models to characterize the impact of specific members of the intestinal microbiota on the host physiology is a promising avenue for dissecting the key pathways involved in these interactions [3, 10].
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