Abstract

A field porcine epidemic diarrhea virus (PEDV) strain, JS2008, was isolated from stool samples of a piglet with acute diarrhea on a vaccinated farm in eastern China. We sequenced and analyzed the complete genome of strain JS2008, which will help increase our understanding of the molecular characteristics of the epidemic PEDV in China.

Highlights

  • A field porcine epidemic diarrhea virus (PEDV) strain, JS2008, was isolated from stool samples of a piglet with acute diarrhea on a vaccinated farm in eastern China

  • Porcine epidemic diarrhea virus (PEDV), a member of the family Coronaviridae, is an enveloped virus with a singlestranded, positive-sense RNA and causes porcine epidemic diarrhea, an enteric disease characterized by acute watery diarrhea, dehydration, vomiting, and high mortality in nursery piglets [1, 2]

  • We sought to analyze the genome sequence of PEDV strain JS2008 and understand its molecular characteristics

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Summary

Introduction

A field porcine epidemic diarrhea virus (PEDV) strain, JS2008, was isolated from stool samples of a piglet with acute diarrhea on a vaccinated farm in eastern China. Porcine epidemic diarrhea virus (PEDV), a member of the family Coronaviridae, is an enveloped virus with a singlestranded, positive-sense RNA and causes porcine epidemic diarrhea, an enteric disease characterized by acute watery diarrhea, dehydration, vomiting, and high mortality in nursery piglets [1, 2]. Outbreaks of PEDV infection have been documented mainly in European and Asian countries since the disease was first recognized in an acute outbreak of diarrhea in pigs [1]. In the autumn of 2010, severe diarrhea in piglets emerged in China, affecting more than 1,000,000 piglets [3].

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