Abstract
ABSTRACTHepatitis B virus (HBV) causes significant global health problems despite the presence of a potential vaccine. HBV chronic cases are increasing rapidly in developing countries like Bangladesh. Here, we report the complete genome sequence of an HBV genotype C strain isolated from a chronic patient identified at an outdoor hospital section.
Highlights
Hepatitis B virus (HBV), a partially double-stranded covalently closed circular DNA virus belonging to the Hepadnaviridae family, is highly contagious and causes severe liver infection in humans [1]
The assembled genome of isolate NHB17003, which has a length of 3,215 bp, comprises four overlapping open reading frames that encode several major proteins such as the surface protein (HBsAg), core protein, polymerase protein, and X protein
The surface protein is encoded with three different segments of independent properties, such as large, middle, and small surface proteins
Summary
Hepatitis B virus (HBV), a partially double-stranded covalently closed circular (ccc) DNA virus belonging to the Hepadnaviridae family, is highly contagious and causes severe liver infection in humans [1]. The assembled genome of isolate NHB17003, which has a length of 3,215 bp, comprises four overlapping open reading frames that encode several major proteins such as the surface protein (HBsAg), core protein, polymerase protein, and X protein.
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