Abstract

We report here the full-length RNA genomic sequence of the bovine viral diarrhea virus (BVDV) strain GX4, isolated from a cow in southern China. Studies indicate that BVDV GX4 belongs to the BVDV-1b subtype. This report will help in understanding the epidemiology and molecular characteristics of BVDV in southern China cattle.

Highlights

  • We report here the full-length RNA genomic sequence of the bovine viral diarrhea virus (BVDV) strain GX4, isolated from a cow in southern China

  • BVDV is a member of the genus Pestivirus in the family Flaviviridae

  • BVDV is classified into two biotypes, cytopathogenic and noncytopathogenic, based on the presence or absence, respectively, of cytopathogenic effects in cell cultures

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Summary

Introduction

We report here the full-length RNA genomic sequence of the bovine viral diarrhea virus (BVDV) strain GX4, isolated from a cow in southern China. Bovine viral diarrhea virus (BVDV) is a positive-sense singlestranded RNA virus, with a genome size of approximately 12.5 kb. BVDV is classified into two biotypes, cytopathogenic and noncytopathogenic, based on the presence or absence, respectively, of cytopathogenic effects in cell cultures. BVDV1 has at least 15 subtypes, and the complete genomic sequences of BVDV-1a, -1b, -1d, -1e, -1m, 1k,, and BVDV-2a and -2b have been reported [3,4,5].

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