Abstract

Toscana virus (TOSV) is an arthropod-borne phlebovirus belonging to the Sandfly fever Naples virus species (genus Phlebovirus, family Bunyaviridae). Here, we report the complete coding sequences of six TOSV strains isolated from human patients having acquired the infection in southeastern France during a 12-year period.

Highlights

  • Toscana virus (TOSV) is an arthropod-borne phlebovirus belonging to the Sandfly fever Naples virus species

  • Lineage A strains have been identified in Italy, France, Algeria, Tunisia, and Turkey [2,3,4,5]; lineage B strains were detected in Spain, Portugal, France, Morocco, and Turkey [6, 7]; lineage C was detected on a molecular basis only in Croatia and Greece

  • Despite the large geographic area where human populations are exposed to TOSV, only 10 full-length sequences were available at the outset of this study, three for lineage A and seven for lineage B; of these 10 sequences, seven originated from sandflies and three from humans

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Summary

Introduction

Toscana virus (TOSV) is an arthropod-borne phlebovirus belonging to the Sandfly fever Naples virus species (genus Phlebovirus, family Bunyaviridae). Toscana virus (TOSV) belongs to the Sandfly fever Naples virus species within the genus Phlebovirus in the family Bunyaviridae. TOSV is an enveloped virus with a single-strand negative-sense RNA genome consisting of three segments (large [L], medium [M],and small [S]).

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