Abstract
Objective To compare the effect on correcting calcium and phosphate metabolic disorder and the impact on quality of life in uremia patients between on-line hemodiafiltration and high-flux hemodialysis. Methods 90 patients with uremia, digital watches were randomly divided into QL-HDF group and HFHD group, Ca2+ , P3+ , serum parathyroid hormone(PTH) level were measured before and after dialysis blood.The survival quality of patients were evaluated by the KDQOL-SFTM1.3 scale.The incidence of adverse reactions were collected.The similarities and differences of two groups were compared. Results The comparison of Ca2+ levels in the two groups before and after dialysis showed no significant difference(P>0.05); Of the QL-HDF group after treatment, P3+ was (1.82±0.19)mmol/L, PTH was (401.6±16.7)pg/L, which were significantly lower than those of QL-HDF group[P3+ (2.14±0.22)mmol/L, PTH(425.0±17.2)pg/L](t=24.256, 21.059, all P 0.05); 6 cases of adverse reactions was in the QL-HDF group (13.33%), 14 cases of adverse reactions was in the HFHD group(31.11%), there was significant difference between the two groups(χ2=5.361, P<0.05). Conclusion The two methods can improve the metabolic disorders of calcium and phosphorus in patients with uremia, and QL-HDF showed stronger ability to remove the ability, and the quality of life is higher, it is worth promoting in clinical practice. Key words: Calcium metabolism disorders; Phosphorus metabolism disorders; Uremia; Hemodiafiltration; Renal dialysis; Quality of life
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