Abstract
Here, we report 40 new whole-genome sequences of influenza A(H1N1)pdm09 viruses isolated from Finnish patients during 2009 to 2014. A preliminary analysis of these and 186 other whole genomes of influenza A(H1N1)pdm09 viruses isolated from hospitalized and nonhospitalized patients during 2009 to 2014 in Finland revealed several viral mutations that might be associated with patient hospitalizations.
Highlights
Human influenza A viruses cause epidemics and pandemics
We sequenced the whole genomes of 40 influenza A(H1N1)pdm09 strains isolated from nonhospitalized and hospitalized patients (Finland, 2009 to 2014) who were diagnosed with influenza A virus infection
A comparative analysis of whole-genome sequences of influenza strains isolated from 56 hospitalized and 170 nonhospitalized Finnish patients revealed 29 missense mutations that might be associated with patient hospitalizations (P Ͻ 0.00005, chi-square test of independence)
Summary
Human influenza A viruses cause epidemics and pandemics (http://www.who.int/topics/influenza/en/). In some cases, infections with A(H1N1)pdm09 viruses resulted in hospitalizations.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
