Clinical study of Simiao pill combined with celecoxib in the treatment of acute gouty arthritis

Abstract

Objective To observe the efficacy of Simiao pill combined with celecoxib in the treatment of acute gouty arthritis(AGA). Methods From January 2015 to January 2017, 70 patients with AGA in the Central Hospital of Luohe were selected and randomly divided into two groups, with 35 cases in each group.The control group received celecoxib treatment, while the treatment group received Simiao pill combined with celecoxib.The treatment course was 7 days in each group.The clinical efficacy and the blood uric acid(UA) changes were observed and compared before and after treatment. Results The total effective rate of the treatment group was 91.4%(32/35), which was remarkably higher than 77.1%(27/35) of the control group, the difference between the two groups was statistically significant(χ2=4.381, P 0.05). After treatment, the level of UA in the treatment group was (402.17±18.43)μmol/L, which was lower than (475.29±37.82)μmol/L in the control group, the difference between the two groups was statistically significant (t=-11.051, P<0.05). Conclusion The clinical efficacy of Simiao pill combined with celecoxib in the treatment of AGA is effective, and is worthy of clinical promotion. Key words: Arthritis, gouty; Medicine, chinese traditional; Combined modality therapy; Drug therapy, combination; Simiao tablet; Celecoxib; Uric acid; Compartive study