Abstract
Background: In Indonesia, East Java ranks second in HIV cases, with 71,909 reported by March 2022. The co-infection of HIV and TB poses significant health challenges, as People Living with HIV ( PLHIV ) are 14-18 times more likely to contract TB, which accelerates HIV progression and increases the risk of death. In 2021, TB was the leading cause of death among PLHIV, with around 187,000 deaths worldwide. Understanding the clinical profile of TB-HIV co-infected patients is essential to improve diagnosis and treatment, particularly in RSUD Dr. Soetomo Surabaya, where this study aims to provide valuable data for reducing co-infection cases in Surabaya and Indonesia. This study is a descriptive retrospective study that uses secondary data from medical records. In this research, 154 TB patients with HIV-AIDS at Dr. Soetomo Surabaya Regional General Hospital were collected through a random sampling technique within a period of 1 year, starting from January 2022 to December 2022. The characteristics of TB-HIV patients were predominantly male, with the majority aged between 18-65 years. The distribution of CD4 risk factors showed that 53% of the patients had very low CD4 levels, followed by 35% with low CD4 levels. Analysis of physical factors such as hemoglobin, leukocyte, and platelet levels revealed that most patients had low hemoglobin levels, with normal leukocyte and platelet counts, showing significant differences between these parameters in TB-HIV patients. This study also demonstrated that the majority of confirmed TB patients with HIV at RSUD Dr. Soetomo exhibited at least one clinical sign, including cough, fever, chronic diarrhea, or weight loss.
Published Version
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