Clinical observation on ambroxol in the treatment of 50 children with pneumonia

Abstract

Objective To investigate the effect of ambroxol hydrochloride in the treatment of children with pneumonia.Methods 100 children with pneumonia in our hospital were randomly divided into the treatment group and the control group,50 cases in each group.The control group was given conventional therapy,the treatment group was treated with ambroxol on the basis of the control group.The treatment effect was compared between the two groups.Results The total effective rate in treatment group was 92％,which was significantly higher than 72％ in the control group(x2 =3.87,P ＜ 0.05).CD4+,CD4+/CD8+ immune factor indexes in the treatment group were significantly higher than those in the control group,IgE was significantly lower than that in the control group(t =11.97,1.95,13.56,all P ＜ 0.05).Extinction time of fever,pulmonary rales,cough and hospital stay in the treatment group were significantly less than those in the control group(t =2.93,5.82,3.56,7.71,all P ＜ 0.05).The adverse reactions between the two groups had no significant difference (x2 =1.21,P ＞ 0.05).Conclusion Ambroxol can enhance the cellular immune function in children with pneumonia,rapidly relieve clinical symptoms,improve the therapeutic effect,and have no adverse reaction. Key words: Ambroxol; Pneumonia; Child; Immunologic factors; Treatment outcome