Abstract

目的 探讨氯吡格雷联合阿司匹林治疗进展性脑梗死的临床疗效。 方法 选取2012年1月至2016年1月在黄石市第二医院神经内科住院治疗的进展性脑梗死患者106例为研究对象,采用随机数字表法分为对照组(55例)和观察组(51例),两组在常规治疗基础上,对照组口服阿司匹林肠溶片100 mg,1次/d;观察组采用氯吡格雷片75 mg和肠溶阿司匹林片100 mg口服,1次/d,疗程14 d。评估两组患者神经功能缺损程度、神经功能障碍康复程度。 结果 治疗后14 d,观察组美国国立卫生研究院卒中量表(NIHSS)评分(8.25±2.76)分,优于对照组的(10.14±2.17)分(P=0.021);治疗后28 d,观察组日常生活活动能力量表Barthel指数(72.31±6.77),优于对照组的(64.35±4.63)(P=0.017)。 结论 氯吡格雷联合阿司匹林治疗进展性脑梗死的临床疗效优于单用阿司匹林。

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