Abstract

Objective To investigate the clinical efficacy and safety of low dose of urokinase combined with sodium ozagrel in treatment of progressive cerebral infarction patients. Methods From 2012 December to December 2014, 100 patients with progressive cerebral infarction were randomly divided into study group and control group with 50 cases in each group. The control group was treated with low molecular dextran and ginkgo leaf injection for treatment, and patients in the study group were treated with low dose urokinase and sodium ozagrel treatment. The neurological condition and adverse reactions of the two groups were detected, analyzed and compared. Results The total efficiency of the patients in study group (94.0%) was significantly higher than that in the control group (74.0%), and the differences were significant(P<0.05). Conclusions Low dose of urokinase combined with sodium ozagrel has good effect on progressive cerebral infarction patients, and with mild adverse reactions, so it is worthy of popularization and application. Key words: Urokinase; Sodium ozagrel; Progressive cerebral infarction

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