Clinical efficacy of noninvasive positive pressure ventilation on elderly chronic obstructive pulmonary patients with respiratory failure

Abstract

Objective To investigate the clinical efficacy of noninvasive positive pressure ventilation for elderly patients with chronic obstructive pulmonary disease and respiratory failure. Methods A total of 64 elderly patients with chronic obstructive pulmonary disease and respiratory failure were collected. The patients were treated with conventional therapy, while using BiPAP ventilator line through the nose and mouth mask bilevel noninvasive positive pressure ventilation therapy, and to give effective care. After treatment for 3d,the p H,PaO2,PaCO2,SaO2 index changes, respiration, heart rate changes and APACHEⅡ,GCS and accessory muscle score were observed.Adverse reactions were recorded. Results Before treatment the PH value of patient was(7.30±0.06), which significantly increased to(7.36±0.03)after treatment, PaO2 values was significantly increased to(43.58±5.54) from(84.52±8.27),SaO2 value was significantly increased to(94.93±5.61)from(74.86±7.25),PaCO 2 value from(71.69±8.48)decreased to(42.55±6.23). There was statistically significant before and after treatment(t=5.98,6.35,4.86,7.23,all P<0.05),respiratory rate,heart rate were significantly improved,showing a significant difference(t=4.87,5.32,all P<0.05),APACHEⅡ,GCS and accessory muscle scores were significantly improved, which APACHEⅡ, accessory muscle score was significantly lower, GCS score was significantly increased, were statistically significant(t=4.09,4.01,4.33,all P<0.05). Conclusion It shows that noninvasive positive pressure ventilation combined with conventional drug therapy can improve elderly patients with chronic obstructive pulmonary disease and respiratory failure in patients with clinical symptoms, increase ventilation and improve hypercapnia, clinical efficacy is better,with no serious adverse reactions. Key words: Respiratory failure; Noninvasive positive pressure ventilation; Pulmonary disease; Chronic obstructive