Clinical effect of sequential radiotherapy and chemotherapy after surgery in the treatment of 40 cases with advanced gastric cancer

Abstract

Objective To analyze and discuss the clinical effect of sequential radiotherapy and chemotherapy in 40 patients with advanced gastric cancer after operation. Methods 80 postoperative gastric cancer patients who received sequential radiotherapy and chemotherapy in our hospital were prospectively analyzed.According to the order of admission, 80 patients were divided into two groups, 40 cases of the control group (chemotherapy) and 40 cases of the observation group (sequential chemotherapy). The clinical effects of the two groups were compared. Results In the observation group, 1 year survival rate and 2-year survival rate (77.50%, 47.50%) were higher than those in the control group (50.00%, 25.00%), there were statistically significant differences between the two groups (χ2=19.20, 32.65, all P<0.05). The incidence rate of adverse reactions of the control group was 12.50%, which was lower than 30.00% of the observation group, there was statistically significant difference between the two groups (χ2=9.15, P<0.05). The mortality rate of the observation group was 32.50%, which was lower than 45.00% of the control group, the difference was statistically significant (χ2=5.29, P<0.05). Conclusion Compared with the simple chemotherapy after the operation of gastric cancer, sequential radiotherapy and chemotherapy can effectively improve the clinical efficacy, significantly reduce the rate of postoperative metastasis and recurrence of gastric cancer, and it is worthy of promoting. Key words: Radiotherapy; Chemotherapy, adjuvant; Stomach neoplasms