Clinical analysis of blood purification technology in the treatment of 23 cases with severe toadstool poisoning

Abstract

Objective To observe the curative effect and experience of blood purification technology in the treatment of severe mushroom poisoning. Methods A total of 23 patients with severe mushroom poisoning in the Central Hospital of Pulandian District of Dalian were collected.On the basis of general therapy (emetic, gastric lavage, oral activated charcoal, catharsis, atropine, adrenal cortical hormone, symptomatic and supportive treatment), the patients were given blood purification therapy: hemoperfusion, 2 hours each time, 1 time every two days; application in series with hemodialysis, hemoperfusion; bedside hemofiltration was performed (8-10)h/ time. Results Of the 23 patients, 22 cases had liver injury (95.7%), 7 cases had renal injury (30.4%), 3 cases had central nervous system damage (13%), and 4 cases had other 17.4%.Hemoperfusion was performed in 22 patients, with an average of (3.6±0.4)times per day, and 19 patients with bedside hemofiltration, with an average of (2.9±0.5)times per patient.Outcome: 21 cases were improved, 2 cases died. Conclusion Blood purification treatment should be done as early as possible for mushroom poisoning patients, and it is an effective method for the treatment of severe mushroom poisoning. Key words: Hemodafitration; Mycotoxicosis; Poisoning; Multiple organ failure