Clinical analysis of 43 congenital TORCH infections in newborns

Abstract

Objective To search for the early clinical manifestations as evidences for prevention and treatment TORCH infections in newborns as early as possible. Methods ELASA was performed to screen specific anti-TORCH ( Toxoplasma gondlii, Cystomegalovirus, Rubella virus, Herpes simplex virus ) Ig-M antibodies.RESULTS Totally 1352 in-patients who were treated in Neonatal Intemaive Care Unit(NICU) of our hospital from January 2007 to June 2008 were retrospectively studied,43 of them had TORCH infections. Cytomegalovirus, rubella and herpes simples virus infections accounted for 48.8% ,32.6% and 18.6%, respectively. None of them had toxoplasma infection. The main clinical manifestations of them were hearing impairment, hyperbilirubinemias and liver dysfuntion,impairment of neurologic system, myocardial impairment, thrombocytopenia, and congenital heart disease. Conclusion TORCH infections can cause multiorgan lesions. Rubella vaccine inoculation, serological screening during pregnancy and early period of newborn, intervention and treatment in the early period are most important. Key words: TORCH infections; Congenital; Newborns11