Abstract

BackgroundMacrotyloma uniflorum Linn (Fabaceae) is a herbaceous plant with annual branches. It is used in kidney stones, inflamed joints, fever, musculoskeletal disorders, sinus wounds and localized abdominal tumors. It is reported as an antioxidant and nutraceutical (forage and food). GC-MS analysis of ethanol extract has led to identification of twenty-eight compounds from M. uniflorum by comparison of their retention indices and mass spectra fragmentation patterns with those stored on the GC-MS computer library.ResultsThe main constituents identified were mome inositol, ethyl alpha-d-glucopyranoside, n- hexadecanoic acid, linoleic acid (9, 12-octadecadienoic acid), its esters and ethyl derivatives, Vitamin E, stigmasterol and 3-beta-stigmast-5-en-3-ol.ConclusionsThe extracts are rich in linoleic acid and its esters, mome inositol and ethyl alpha-d-glucopyranoside; therefore, this plant can be medicinally beneficial as an antioxidant, in diabetes and its related disorders.Electronic supplementary materialThe online version of this article (doi:10.1186/s13588-014-0013-y) contains supplementary material, which is available to authorized users.

Highlights

  • Macrotyloma uniflorum Linn (Fabaceae) is a herbaceous plant with annual branches

  • It has been widely used in the treatment of kidney stones, inflamed joints, fever, musculoskeletal disorders, sinus wounds and localized abdominal tumors [2,3]

  • Chemical composition GC-MS analysis of ethanol extract led to the identification of twenty-eight compounds from M. uniflorum (Table 1, Figure 1)

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Summary

Introduction

Macrotyloma uniflorum Linn (Fabaceae) is a herbaceous plant with annual branches It is used in kidney stones, inflamed joints, fever, musculoskeletal disorders, sinus wounds and localized abdominal tumors. Macrotyloma uniflorum (synonym: Dolichos biflorus Linn.) belonging to the family Fabaceae is commonly known as Kulthi in Hindi and horse gram in English It is a herbaceous plant with annual branches, sub-erect or twining, leaflets of 2.5 to 5 cm. The genus Macrotyloma comprises about 25 species, most of which are restricted to Africa of which four have been identified as M. uniflorum, M. stenocarpum, M. verrucosum and M. benadirianum [1] It has been widely used in the treatment of kidney stones, inflamed joints, fever, musculoskeletal disorders, sinus wounds and localized abdominal tumors [2,3]. To the best of the authors' knowledge, no published literature exists about the chemical contents of the ethanol extract

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