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Abstract
This chapter describes the evolving role of clinical trial registries and results databases. The first part describes the important public health policy goals of registration and results reporting, its history, and key policies in the United States and abroad. The second part focuses on practical issues, policies, and procedures for submitting data to and using data from ClinicalTrials.gov, the largest publicly available clinical trials database in the world. The future role of systematic sharing of individual participant data also is discussed.
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