Abstract

Molecular characterization of GM plants is a core component of the overall pre-commercialization risk assessment process. It applies to GM plants that have been screened to eliminate off-types resulting from unintended effects such as genomic rearrangements, deletions, gene silencing, or pleiotropic effects after many propagation cycles. The purpose of the molecular characterization of the selected GM plants is to provide essential background knowledge that can guide the assessment of the plant phenotype in relation to potential impacts on food, feed, and environmental safety. Molecular characterization of GM plants is a mandatory regulatory requirement. The chapter provides a summary of the most common analytical methodologies used to acquire information and data relevant to molecular characterization.

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