Abstract
Oxidative stress (OS) is a well-known factor contributing to male infertility, with reactive oxygen species (ROS) impairing spermatogenesis, sperm motility, and membrane and DNA integrity. Since high levels of ROS have been strongly associated with male reproductive dysfunction, there is an urgent clinical need for inexpensive and easy-to-perform assays measuring ROS levels in semen as an important part of the initial evaluation as well as follow-up of subfertile or infertile patients. The aim of this chapter is to provide information on the nitroblue tetrazolium assay for the measurement of intracellular superoxide production in spermatozoa that may have a significant clinical utility in identifying men with impaired fertility associated with seminal OS.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: Oxidants, Antioxidants, and Impact of the Oxidative Status in Male Reproduction
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
