Abstract
The accurate registration of positron emission tomography (PET) and magnetic resonance (MR) images provides important information on structure/function relationships, permits precise anatomically based region of interest definition, and may allow partial volume correction of the PET study. There are compelling reasons for merging high-resolution anatomical information from magnetic resonance (MR) imaging with the functional images attainable with positron emission tomography (PET) .The ideal solution to this intermodality image registration is to acquire PET and MR scans simultaneously with imaging systems that are fixed relative to each other, which will permit near-perfect image registration. This is particularly important for studies of small brain structures or in animal studies. A prototype PET system has been developed that permits PET and MR images to be acquired simultaneously, which has been discussed in the chapter.
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