Abstract
2-Oxoaldehydes (AGs) are important precursors that are frequently used for the construction of different biologically important scaffolds. AGs possess both ketone and aldehyde functional groups with different reactivity that undergoes various organic transformations to develop different methods for carbon-heteroatom bond formations. Reactions of AGs were performed in three different ways: (1) reactions took place in the more reactive aldehyde group, (2) reactions took place from keto group of the AG without affecting the aldehydic group, and (3) reaction take place from the participation of both aldehyde and ketone groups of AG to provide two atoms of the heterocyclic rings.
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