Chapter 27 - Skeletal Impact of Soy Protein and Soy Isoflavones in Humans

Abstract

Ethnic differences in bone make some groups more susceptible than others to osteoporotic fractures. Elderly Taiwanese and mainland Chinese have a lower hip fracture incidence than Caucasians, leading clinicians to speculate that isoflavone-containing soy protein may be responsible. Researchers have posited that soy protein may lessen bone loss in midlife women, but most recent studies have not substantiated favorable skeletal effects using soy foods, soy protein, or extracted isoflavones. Although published studies do not provide definitive evidence that soy isoflavones can prevent or treat osteoporosis, clinicians can nevertheless recommend soy foods because of their excellent nutrient profile and overall health benefits.