Abstract
This chapter introduces the basic principle of biomineralization and the theory of biological mineralization interface control, and the progress of natural bone formation and mineralization. Natural bone is composed of mineralized collagen (MC) by a series of self-assembly and molecular rearrangement and subsequent processing and modification of the formation. The natural bone formation and biological mineralization are closely related. Preliminary mineralization of collagen and its surface nucleation sites. Biomimetic preparation of hydroxyapatite MC fibers are a long-sought bone graft material in many laboratories because of their composition, structure, and properties. Natural bones are similar and have good bioactivity and biodegradability. There are many reports on the structure, properties, synthesis mechanism and application of collagen/HA and with the increasing acceptance of biomimetic materials, several collagen and hydroxyapatite composite materials have gained market access permits, and more and more doctors are accepting them.
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