Abstract
The discovery of antibiotics led to a reduction in mortality and morbidity due to infectious diseases. However, their overuse has been contributed to rapidly increasing bacterial resistance. Antibiotic resistance is the ability of microorganisms, including bacteria, to resist the effects of an antibiotic to which they were once sensitive. It is well known that bacteria, parasites, protozoa, and fungi develop resistance when exposed to antibiotics. The microorganisms that survive and multiply cause more harm, even when treated with certain antimicrobials. Moreover, the emergence of resistance has been rapid and limited the useful life of many antibiotics or other antiparasitic drugs. Concerns about the increased antibiotic resistance of microorganisms commonly found in human patients, due to excessive use of antibiotics in humans and/or animals for the treatment of diseases or in animals as dietary growth promoters have been raised worldwide. The aim of this chapter is to further elucidate the matter of antibiotic or natural substances resistance and explore possible mechanisms of action of herbal compounds.
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