Abstract

Cancer treatment is one of the major challenges of modern medicine. Hyperthermia, a technique in which the body temperature is raised above the normal level, is a complementary approach for the treatment of cancer. The response of cancer cells to radiation and chemotherapy can be enhanced by increasing the tumor temperature. Advances in nanotechnology have made possible the diagnosis and treatment of different types of cancer with minimal side effects. Nanoparticles are used to induce localized heating within tumors. Nanoparticle-induced heat therapy can be used for detection of the tumor and delivery of a pharmacological active drug in the tumor site. Hyperthermia can be induced either through a laser radiation or an applied magnetic field. The magnetic particles can be used as heating mediators and this novel strategy helps in improving tumor treatment and it can also be used for magnetic resonance imaging. Similarly, the unique optical property of noble metal nanoparticles has been used for innovative light-based approaches for cancer treatment. It was reported that hybridization of noble metal (Au, Ag) and magnetic iron oxide nanoparticles enhanced the effectiveness of hyperthermia, in comparison with the individual nanoparticles.

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