Abstract

The ongoing 21st century SARS-CoV-2 pandemic has endangered global health and alarmed the scientific community at an unprecedented rate. Being a member of Coronaviridae family, the SARS-CoV-2 virus contains an enveloped, single-stranded, positive-sense RNA genome that typically affects the respiratory tract of mammals, including humans, leading to mild to severe respiratory tract infections. The ever costly and time-consuming process of drug discovery has led researchers to use in silico approaches to find potential drug candidates with reference to molecular and signaling pathways associated with the disease. Many studies on in silico tools are used to virtually screen small molecule databases for drug discovery against COVID-19.

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