Abstract
Lifespan prolongation is a long-held desire of mankind. With technological advances, the mechanism of aging has been unraveled over the years. Along with an increase in understanding of the aging process, the development and execution of antiaging interventions are no longer mere concepts, but are getting closer to reality. To develop an intervention to tackle aging and age-associated ailments, the first step is to select a feasible approach by which the aging process can be modulated. The objective of this chapter is to introduce different theoretical frameworks for understanding the aging process, and to discuss their implications for the development of biogerontological interventions. These frameworks will likely constitute the conceptual foundation of antiaging therapies that will be designed by using the technologies which will be covered in subsequent chapters of this book.
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