Abstract

Background: The incidence rate of syphilis has been increasing in recent years. Ocular syphilis can manifest at any stage of syphilis, either with or without Human Immunodeficiency Virus (HIV) co-infection. Case Illustration: A 52-year-old man presented with a complaint of blurred vision persisting for the past 6 months. Visual examination revealed NLP (no light perception) in the right eye and 6/30 in the left eye. Syphilis serology testing was positive. Patient were diagnosed with latent syphilis with ocular syphilis, along with stage I HIV infection. Patient were treated with benzathine penicillin also with antiretroviral therapy for the HIV infection. Conclusion: Syphilis and HIV often occur together and can influence each other. Syphilitic ulcers can serve as the port of entry for HIV infection. In HIV-infected individuals with syphilis, the symptoms of syphilis can be varied due to the immunocompromised state. Benzathine penicillin G is a first-line therapy for ocular syphilis.

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