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Biobanking and risk assessment: a comprehensive typology of risks for an adaptive risk governance

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Abstract
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Biobanks act as the custodians for the access to and responsible use of human biological samples and related data that have been generously donated by individuals to serve the public interest and scientific advances in the health research realm. Risk assessment has become a daily practice for biobanks and has been discussed from different perspectives. This paper aims to provide a literature review on risk assessment in order to put together a comprehensive typology of diverse risks biobanks could potentially face. Methodologically set as a typology, the conceptual approach used in this paper is based on the interdisciplinary analysis of scientific literature, the relevant ethical and legal instruments and practices in biobanking to identify how risks are assessed, considered and mitigated. Through an interdisciplinary mapping exercise, we have produced a typology of potential risks in biobanking, taking into consideration the perspectives of different stakeholders, such as institutional actors and publics, including participants and representative organizations. With this approach, we have identified the following risk types: economic, infrastructural, institutional, research community risks and participant’s risks. The paper concludes by highlighting the necessity of an adaptive risk governance as an integral part of good governance in biobanking. In this regard, it contributes to sustainability in biobanking by assisting in the design of relevant risk management practices, where they are not already in place or require an update. The typology is intended to be useful from the early stages of establishing such a complex and multileveled biomedical infrastructure as well as to provide a catalogue of risks for improving the risk management practices already in place.

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  • Cite Count Icon 1
  • 10.1007/978-3-642-22266-5_6
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The African continent is likely to be highly affected by the consequences of climate change. The ensuing projected changes in the ecological system such as decreasing water availability and higher amplitudes of droughts and floods require responses from the social system, i.e. adaptation measures. Even though climate modelling is still plagued by high uncertainty, models suggest a reduction of precipitation and runoff for South Africa. This poses a major threat for South Africa, which depends heavily on surface water and whose water resources are already under stress. Adaptive governance has been proposed as an approach that provides a way to cope with rising uncertainty and environmental change. Against the background of decreasing water availability and in addition to technical solutions, adaptive water governance structures can serve as an important element for increasing water use efficiency, adaptive capacity and resilience of the water sector. The first part of the paper takes a conceptual approach towards adaptive water governance. It suggests characterizing adaptive water governance by referring to and merging elements of good governance, water governance and adaptive governance. In the second part of the paper, some of the elements of adaptive water governance are examined with regard to their relevance for South Africa’s water governance reforms. The paper concludes that, on the one hand, progress can be attested with regard to (1) a high level of flexibility built in the national water legislation, especially the National Water Act, (2) the provision of buffer capacities regarding institutions for solving water conflicts (redundancy), (3) the high level of participation of stakeholders at many levels and (4) the provision of equitable access to water. On the other hand, some (unintended) negative implications of these developments are documented. Among them are (1) the time-consuming processes of elaborating procedures and guidelines in the process of implementation, (2) the potentially negative effects of functional overlaps of CMA and regional offices of DWA, (3) effectively involving relevant stakeholders and (4) the lacking long-term sustainability of water infrastructure due to lack of capacity and capital.KeywordsAdaptationAdaptive governanceWater governanceGood governanceResilienceSouth Africa

  • Research Article
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  • 10.1080/10807030390247132
Essays in Commemoration of the 20th Anniversary of the National Research Council's Risk Assessment in the Federal Government: Managing the Process
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  • Human and Ecological Risk Assessment: An International Journal
  • Barry L Johnson + 1 more

The publication in 1983 of the National Research Council's report Risk Assessment in the Federal Government: Managing the Process was a milestone in the development of risk assessment and risk management practices and policies. The report quickly became known as the “Red Book” because of its vivid red cover. The Red Book's recommendations on how to improve institutional practice of risk assessment and management helped shape risk policy and practices at regulatory agencies such as the U.S. Environmental Protection Agency. In commemoration of the Red Book's 20th anniversary, essays were solicited from members of the original Red Book Committee and other experts in risk assessment. The essays comprising this special issue of the Journal of Human and Ecological Risk Assessment provide a valuable historical record of the Red Book's development, import, and subsequent impact on the continuing evolution of risk assessment. The set of essays in this issue describe the Red Book's past and current impact on the evolution of cancer risk assessment, non-cancer risk assessment, ecological risk assessment, and risk assessment for occupational safety and health. In the aggregate, the essays express strong support for the positive impact of the Red Book, but also express concern about current risk assessment and risk management policies and practices. Perhaps the time has arrived for Red Book II.

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  • Supplementary Content
  • 10.22409/ppga.2020.mp.86586319153
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  • Research Article
  • Cite Count Icon 7
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  • Mar 14, 2022
  • International Journal of Economics and Financial Issues
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  • NDU Journal
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This research investigates the impact of risk assessment strategies on research and development (R&D) projects in the defence sector. The researchers performed comprehensive analyses of risk management frameworks and practices employed by leading defence organisations globally, including the US Department of Defence, UK Ministry of Defence, Canadian Department of National Defence, and India's Innovation for Defence Excellence and critically analysed the key risk assessment factors and best risk management practices. This research developed a tailored risk assessment framework specific to Pakistan's defence R&D projects through extensive case study analyses and fifty semi-structured interviews with people working with defence organisations. The proposed framework comprises seven essential steps, from work breakdown structure development to continuous risk monitoring. This research aimed to provide a systematic and unified approach to risk management by addressing the gaps and investigating international and regional approaches.

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