Abstract
The use of transaminases for the incorporation of deuterium and tritium in chiral amines starting from prochiral ketone precursors has been demonstrated. Efficient labeling was demonstrated using a variety of ketone substrates. Amplification of the labeled product was observed, with tritium incorporation enriched up to 2.8X the statistically expected levels of labeling.
Full Text
Published Version
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call