Abstract
The consequence of the demographic aging of the population is an increase in the surgical pathology of the elderly. Local anesthetics (LA) play an important role in providing anesthetic care to this category of patients. Features of pharmacokinetic processes in the elderly, including the processes of absorption, distribution, metabolism, and excretion, underlie the change in the pharmacodynamic effects of LA. Elderly patients are at a higher risk of adverse reactions. This is due to physiological changes associated with the aging process, as well as patients’ comorbidity. Patients suffering from the senile asthenia syndrome, cardiovascular diseases, and impaired function of the excretory organs have the highest risks.
Published Version
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