Abstract
Abstract Objective: To investigate the impact of human papillomavirus (HPV) vaccination programs on the incidence of oral cancers and other related pathologies. Materials and Methods: A cross-sectional study was conducted with a sample size of 500 participants aged 18–35 years, recruited from urban and rural healthcare centers. Data were collected through questionnaires and medical records, analyzing the incidence of oral cancers and other pathologies in vaccinated versus nonvaccinated individuals. Statistical analysis was performed using chi-square tests and logistic regression models. Results: The study found a significant reduction in the incidence of oral cancers and other related pathologies among vaccinated individuals compared with nonvaccinated individuals (P < 0.05). Specifically, the incidence of HPV-positive oropharyngeal cancers was notably lower in the vaccinated group than in the nonvaccinated group. Logistic regression analysis confirmed that vaccination was a significant protective factor against developing oral cancers (odds ratio = 0.45, 95% confidence interval = 0.30–0.68). Conclusion: HPV vaccination programs are associated with a significant reduction in the incidence of oral cancers and related pathologies. These findings support the continued promotion and expansion of HPV vaccination programs as a public health strategy to prevent oral cancers.
Published Version
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