Analysis of the efficacy of lactobacillus vaginalis capsule in the treatment of senile vaginitis

Abstract

Objective To explore the effect of lactobacillus vaginal capsule in the treatment of senile vaginitis. Methods From January 2017 to February 2018, 100 elderly patients with vaginitis in the Second People's Hospital of Haining were selected in the study. They were randomly divided into observation group and control group according to the digital table, with 50 cases in each group. The observation group was treated by lactobacillus vagina capsule, and the control group was treated by compound metronidazole suppository. The clinical effects of the two groups were compared. Results The total effective rate of the observation group (96.00%) was significantly higher than that of the control group(76.00%), the difference was statistically significant(χ2=12.547, P 0.05], and there were statistically significant differences in vaginal pH of the two groups before and after treatment(t=8.204, 5.112, all P<0.05), the vaginal pH of the observation group after treatment was significantly lower than that of the control group, the difference was statistically significant[(4.49±0.11) vs. (5.76±0.37), t=5.024, P<0.05]. In the observation group, only 1 case had recurrence at 2 months after treatment, and no recurrence was observed at 3 months and 6 months after treatment, the recurrence rate was 2.00%. In the control group, there were 2 cases, 4 cases, 6 cases had recurrence at 2 months, 3 months and 6 months after treatment, and the recurrence rate was 24.00%. The recurrence rate of the observation group was significantly lower than that of the control group (χ2=25.634, P<0.05). Conclusion Lactobacillus vaginal capsule in the treatment of senile vaginitis has curative effect is distinct, the recurrence rate is low, also the use process is very simple, has high clinical application value. Key words: Vaginitis; Lactobacillaceae; Capsules; Metronidazole; Suppository; Recurrence; Comparative effectiveness research; Aged