Abstract
The stability of any pharmaceutical compound is most desired quality that determines its shelf life and effectiveness. The stability can be correlated to structural and bonding properties of compound and any variation arise in these properties can be easily determined by spectroscopic analysis. The present study was aimed to evaluate the impact of biofield treatment on these properties of four pharmaceutical compounds such as urea, thiourea, sodium carbonate, and magnesium sulphate, using spectroscopic analysis. Each compound was divided into two groups, referred as control and treatment. The control groups remained as untreated and treatment group of each compound received Mr. Trivedi’s biofield treatment. Control and treated samples of each compound were characterized using Fourier- Transform Infrared (FT-IR) and Ultraviolet-Visible (UV-Vis) spectroscopy. FT-IR spectra of biofield treated urea showed the shifting of C=O stretching peak towards lower frequency (1684→1669 cm-1) and N-H stretching peak towards higher frequency (3428→3435 cm-1) with respect to control. A shift in frequency of C-N-H bending peak was also observed in treated sample as compared to control i.e. (1624→1647 cm-1). FT-IR spectra of thiourea showed upstream shifting of NH2 stretching peak (3363→3387 cm-1) as compared to control, which may be due to decrease in N-H bond length. Also, the change in frequency of N-C-S bending peak (621→660 cm-1) was observed in treated thiourea that could be due to some changes in bond angle after biofield treatment. Similarly, treated sample of sodium carbonate showed decrease in frequency of C-O bending peak (701→690 cm-1) and magnesium sulphate showed increase in frequency of S-O bending peak (621→647 cm-1) as compared to control, which indicated that bond angle might be altered after biofield treatment on respective samples. UV-Vis spectra of biofield treated urea showed shift in lambda max (λmax) towards higher wavelength (201→220 nm) as compared to control sample, whereas other compounds i.e. thiourea, sodium carbonate, and magnesium sulphate showed the similar λmax to their respective control. These findings conclude that biofield treatment has significant impact on spectral properties of tested pharmaceutical compounds which might be due to some changes happening at atomic level of compounds, and leading to affect the bonding and structural properties of compounds.
Highlights
Pharmaceutical industries are an important component of health care systems which are largely driven by scientific discovery and development of various chemical and biological agents for human and animal health
It could be due to alteration in bond angle of C-N-H in urea after biofield treatment [39]
The results of present study showed that there has significant impact of biofield treatment on spectral properties of urea, thiourea, sodium carbonate, and magnesium sulphate
Summary
Pharmaceutical industries are an important component of health care systems which are largely driven by scientific discovery and development of various chemical and biological agents for human and animal health. The pharmaceutical industry is based primarily upon many organic and inorganic chemicals, which are used as raw materials, serve as reactants, reagents, catalysts, counter ions and solvents. These chemicals exhibit a wide range of pharmacological activity and toxicological properties [1]. Inorganic compounds play an important role as counter ions in drugs, which influence the solubility, stability, and hygroscopicity of active pharmaceutical ingredients [2]. The compounds selected in this study for biofield treatment are urea, thiourea, sodium carbonate and magnesium sulphate, which have wide applications in pharmaceutical industry
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