Abstract
Volatile organic compounds (VOCs) released by food serve as monitoring indicators during fermentation. Thus the demand for highly sensitive and selective biosensors to VOCs is increasing. The current work proposed a novel nano-colorimetric sensor array (nano-CSA) composed of nano-chemo-responsive materials (CRMs) to quantify volatile alcohols (VAs) in the kombucha tea extract fermentation process. The density-functional theory results suggest that CRMs sensitive to VAs have small energy level differences. The higher the energy of the substance itself, the greater the density of the electron cloud and the stronger the reactivity. The higher the binding energy value, the more stable the molecule structure. The larger the angle and the shorter the centroid distance between CRMs and VAs, promote their effective integration. The work confirmed that the CRM-based nano-CSA is crucial in differentiating VAs employed to evaluate the kombucha tea extract fermentation degree with a 98.99% of variance contribution rate by principal component analysis.
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