Abstract
Uterine adenosarcoma is a rare malignancy. It is defined as a biphasic tumor composed of both sarcomatous stroma and benign epithelial components. When the sarcomatous component occupies more than 25 % of the tumor then it is referred to as the sarcomatous overgrowth which accounts to about 10% of uterine adenosarcoma cases [1]. Usually, adenosarcoma is considered a tumor of low malignant potential. But the sarcomatous overgrowth variant presents as a high-grade sarcoma and so reduces the survival rate of the patient.
Highlights
Uterine adenosarcoma is a rare malignancy. It is defined as a biphasic tumor composed of both sarcomatous stroma and benign epithelial components
When the sarcomatous component occupies more than 25 % of the tumor it is referred to as the sarcomatous overgrowth which accounts to about 10% of uterine adenosarcoma cases [1]
In its typical form, comparable to the low – grade endometrial stromal sarcomas, adenosarcomas are considered of low malignant potential [2]
Summary
It is defined as a biphasic tumor composed of both sarcomatous stroma and benign epithelial components. When the sarcomatous component occupies more than 25 % of the tumor it is referred to as the sarcomatous overgrowth which accounts to about 10% of uterine adenosarcoma cases [1]. A diagnosis of Adenosarcoma with sarcomatous overgrowth and rhabdomyoblastic differentiation was made, indicating poor prognosis for the patient and warranting definitive empirical management. Adenosarcoma of Uterus with Sarcomatous Overgrowth and Rhabdomyoblastic Differentiation - A Rare Pathological Entity. A diagnosis of Adenosarcoma with sarcomatous overgrowth with rhabdomyoblastic differentiation, based on morphology (Rhabdoid cell morphology) and confirmed on immunohistochemistry (Desmin & Myogenin both +ve) with FIGO STAGE-IB (Tumor confined to uterine corpus with
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